Repair of UV dimers in skin DNA of patients with basal cell carcinoma.

@article{Segerbck2008RepairOU,
  title={Repair of UV dimers in skin DNA of patients with basal cell carcinoma.},
  author={Dan Segerb{\"a}ck and Malgorzata Strozyk and Erna Snellman and Kari Hemminki},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2008},
  volume={17 9},
  pages={
          2388-92
        }
}
Epidemiologic studies suggest that exposure to sunlight is the primary etiologic agent for basal cell carcinoma. Formation of UV-induced DNA damage is believed to be a crucial event in the process leading to skin cancer. In this study, repair of photoproducts in DNA was followed in the skin of patients with basal cell carcinoma and control subjects. The subjects were exposed to 800 J/m(2) Commission Internationale de 1'Eclairag of solar-simulating radiation on buttock skin. Biopsies were taken… CONTINUE READING

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