Repair of DNA damage after exposure to 4-nitroquinoline-1-oxide in heterokaryons derived from xeroderma pigmentosum cells.

@article{Zelle1980RepairOD,
  title={Repair of DNA damage after exposure to 4-nitroquinoline-1-oxide in heterokaryons derived from xeroderma pigmentosum cells.},
  author={Bauke Zelle and Dirk Bootsma},
  journal={Mutation research},
  year={1980},
  volume={70 3},
  pages={
          373-81
        }
}
Xeroderma pigmentosum (XP) cells are deficient in the repair of damage induced by ultraviolet irradiation. Excision-repair-deficient XP cell strains have been classified into 7 distinct complementation groups, according to results of studies on cell fusion and UV irradiation. XP cells are not only abnormally sensitive to UV, but also to a variety of chemical carcinogens, including 4-nitro-quinoline-1-oxide (4NQO). Complementation analysis with XP strains from 4 different complementation groups… CONTINUE READING
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