Repaglinide-loaded solid lipid nanoparticles: effect of using different surfactants/stabilizers on physicochemical properties of nanoparticles

@inproceedings{Ebrahimi2015RepaglinideloadedSL,
  title={Repaglinide-loaded solid lipid nanoparticles: effect of using different surfactants/stabilizers on physicochemical properties of nanoparticles},
  author={Hossein Ebrahimi and Yousef Javadzadeh and Mehrdad Hamidi and Mohammad Barzegar Jalali},
  booktitle={DARU Journal of Pharmaceutical Sciences},
  year={2015}
}
Repaglinide is an efficient anti-diabetic drug which is prescribed widely as multi-dosage oral daily regimens. Due to the low compliance inherent to each multi-dosage regimen, development of prolonged-release formulations could enhance the overall drug efficacy in patient populations. Repaglinide-loaded solid lipid nanoparticles (SLNs) were developed and characterized in vitro. Various surfactants were used in this study during the nanocarrier preparation procedure and their corresponding… CONTINUE READING

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