Reoxygenation-induced rigor-type contracture.

@article{Ladilov2003ReoxygenationinducedRC,
  title={Reoxygenation-induced rigor-type contracture.},
  author={Yury Ladilov and Ozkan Efe and Claudia Schaefer and Bettina Rother and Sascha Andreas Kasseckert and Yaser Abdallah and Karsten Meuter and Klaus Dieter Schl{\"u}ter and Hans Michael Piper},
  journal={Journal of molecular and cellular cardiology},
  year={2003},
  volume={35 12},
  pages={
          1481-90
        }
}
The hypothesis tested was that reoxygenation-induced contracture of myocardial cells, a form of reperfusion injury, can be due to a rigor-type mechanism. Isolated adult cardiomyocytes were exposed to 30- or 60-min anoxia (pH 6.4) and reoxygenation (pH 7.4). In cardiomyocytes, cytosolic Ca(2+) and cell length, and in isolated rat hearts left ventricular end-diastolic pressure (LVEDP) were measured. During reoxygenation, cardiomyocytes developed contracture. When energy recovery was slowed down… CONTINUE READING
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