Reovirus Protein sNS Binds in Multiple Copies to Single-Stranded RNA and Shares Properties with Single-Stranded DNA Binding Proteins


Reovirus nonstructural protein sNS interacts with reovirus plus-strand RNAs in infected cells, but little is known about the nature of those interactions or their roles in viral replication. In this study, a recombinant form of sNS was analyzed for in vitro binding to nucleic acids using gel mobility shift assays. Multiple units of sNS bound to single… (More)


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