Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement.


We recently demonstrated that stress-induced cognitive deficits in rats do not correlate with hippocampal neuronal loss. Working on the premise that subtle structural changes may however be involved, we here evaluated the effects of chronic stress on hippocampal dendrite morphology, the volume of the mossy fiber system, and number and morphology of synapses… (More)