Reorganization of the ependyma during axolotl spinal cord regeneration: changes in intermediate filament and fibronectin expression.

@article{OHara1992ReorganizationOT,
  title={Reorganization of the ependyma during axolotl spinal cord regeneration: changes in intermediate filament and fibronectin expression.},
  author={Catherine M O'Hara and M W Egar and Ellen A. G. Chernoff},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1992},
  volume={193 2},
  pages={103-15}
}
Changes in intermediate filament content and extracellular matrix material showed that the injury response of ependymal cells in lesioned axolotl spinal cord involves an epithelial-to-mesenchymal transformation, and that fibrous astrocytes are excluded from the remodeling lesion site. Antibody localization was used to visualize cytokeratin-, vimentin-, and glial fibrillary acidic protein- (GFAP-) containing intermediate filaments, as well as the adhesive glycoprotein fibronectin. In normal… CONTINUE READING

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