Reorganization of the Golgi complex in association with mitosis: redistribution of mannosidase II to the endoplasmic reticulum and effects of brefeldin A.

@article{Thyberg1992ReorganizationOT,
  title={Reorganization of the Golgi complex in association with mitosis: redistribution of mannosidase II to the endoplasmic reticulum and effects of brefeldin A.},
  author={Johan Thyberg and Stanisław Moskalewski},
  journal={Journal of submicroscopic cytology and pathology},
  year={1992},
  volume={24 4},
  pages={495-508}
}
Previous studies have shown that the Golgi complex is broken down into dispersed clusters of vesiculotubular elements as mammalian cells enter mitosis and is reformed in each daughter cell in telophase/cytokinesis. In the present investigation, mannosidase II (a membrane-bound enzyme involved in oligosaccharide processing) was used as a marker to explore the fate of the Golgi complex in dividing L929 and CHO cells in some additional detail. Immunofluorescence microscopy demonstrated a juxta- or… CONTINUE READING