Reorganization of remote cortical regions after ischemic brain injury: a potential substrate for stroke recovery.

@article{Frost2003ReorganizationOR,
  title={Reorganization of remote cortical regions after ischemic brain injury: a potential substrate for stroke recovery.},
  author={Shawn B. Frost and Scott Barbay and Kathleen Friel and Erik J. Plautz and Randolph J. Nudo},
  journal={Journal of neurophysiology},
  year={2003},
  volume={89 6},
  pages={
          3205-14
        }
}
Although recent neurological research has shed light on the brain's mechanisms of self-repair after stroke, the role that intact tissue plays in recovery is still obscure. To explore these mechanisms further, we used microelectrode stimulation techniques to examine functional remodeling in cerebral cortex after an ischemic infarct in the hand representation of primary motor cortex in five adult squirrel monkeys. Hand preference and the motor skill of both hands were assessed periodically on a… Expand
Behavioral and neurophysiological effects of delayed training following a small ischemic infarct in primary motor cortex of squirrel monkeys
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Key findings from neuroimaging studies in human stroke patients are presented, which suggest that the role of contralesional motor hemisphere in supporting recovered function depends on factors such as time since stroke, lesion location and anatomical region. Expand
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