Reorganization of metastamiRs in the evolution of metastatic aggressive neuroblastoma cells

@article{Khan2015ReorganizationOM,
  title={Reorganization of metastamiRs in the evolution of metastatic aggressive neuroblastoma cells},
  author={F. H. Khan and V. Pandian and S. Ramraj and S. Aravindan and T. Herman and N. Aravindan},
  journal={BMC Genomics},
  year={2015},
  volume={16}
}
BackgroundMetastamiRs have momentous clinical relevance and have been correlated with disease progression in many tumors. In this study, we identified neuroblastoma metastamiRs exploiting unique mouse models of favorable and high-risk metastatic human neuroblastoma. Further, we related their deregulation to the modulation of target proteins and established their association with clinical outcomes.ResultsWhole genome miRNA microarray analysis identified 74 metastamiRs across the manifold of… Expand
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