Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program.

@article{Stam2012RenshawCI,
  title={Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program.},
  author={Floor J Stam and Timothy J. Hendricks and Jingming Zhang and Eric J. Geiman and C{\'e}dric Francius and Patricia A. Labosky and Fr{\'e}d{\'e}ric Clotman and Martyn Goulding},
  journal={Development},
  year={2012},
  volume={139 1},
  pages={179-90}
}
The spinal cord contains a diverse array of physiologically distinct interneuron cell types that subserve specialized roles in somatosensory perception and motor control. The mechanisms that generate these specialized interneuronal cell types from multipotential spinal progenitors are not known. In this study, we describe a temporally regulated transcriptional program that controls the differentiation of Renshaw cells (RCs), an anatomically and functionally discrete spinal interneuron subtype… CONTINUE READING
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