Renovascular hypertension—is it fibromuscular dysplasia or Takayasu arteritis

@article{Tullus2012RenovascularHI,
  title={Renovascular hypertension—is it fibromuscular dysplasia or Takayasu arteritis},
  author={Kjell Tullus},
  journal={Pediatric Nephrology},
  year={2012},
  volume={28},
  pages={191-196}
}
  • K. Tullus
  • Published 1 February 2013
  • Medicine
  • Pediatric Nephrology
Renovascular hypertension (RVH) can be caused by many different diseases, with the most common being fibromuscular dysplasia (FMD) and Takayasu arteritis (TA). A strikingly different diagnostic pattern is seen in children with RVH from different parts of the world. In Europe and North America, these children are mainly diagnosed as having FMD while in Asia and South Africa they will most often get a diagnosis of TA. When comparing the clinical diagnosis for FMD and TA, it becomes obvious that… 
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39 Citations

Management of the renovascular disease in children with Takayasu arteritis
TLDR
Patients with inactive disease have a more successful outcome and experience fewer complications from the intervention than those with active on-going inflammation.
Fibromuscular Dysplasia: From a Rare Cause of Renovascular Hypertension to a More Frequent Systemic Arterial Disease
TLDR
The development of the US and European/International FMD registries and associated studies will undoubtedly shed new light on FMD and allow substantial progress in the understanding and management of the disease in the next decade.
An Update on Childhood-Onset Takayasu Arteritis
TLDR
This article aims at providing a comprehensive review of childhood-onset TAK with a focus on recent publications, and recommends TNFα- or interleuking (IL)-6-inhibitors with improved disease control.
Posterior reversible encephalopathy syndrome caused by presumed Takayasu arteritis
TLDR
A 5-year-old girl with presumed TA who presented with PRES and chronic total occlusion in the renal artery is reported, and the confirmatory diagnosis of TA was based on the pathologic findings of the renal arteries.
Angioplasty for recurrent renal artery stenosis in flare‐up of Hashimoto's thyroiditis
TLDR
A 16‐year‐old girl presenting with RVH due to recurrent and novel RAS in Hashimoto's thyroiditis (HT) flare‐up is reported, and after treatment with thyroxin and percutaneous transluminal renal angioplasty (PTRA), she was free of hypothyroidism and systemic hypertension.
High prevalence of extrarenal artery involvement in children with fibromuscular dysplasia – a single-center experience
TLDR
The results of this study suggest that pediatric FMD is a generalized arterial condition, and the patients may need screening for both renal as well as nonrenal manifestations of the disease.
Pitfalls in diagnosing and treating children with renal artery hypertension
TLDR
The case presentation of a 12-year-old boy with hyponatremic hypertensive syndrome due to unilateral renovascular disease and the diagnosis of this child, which the authors give as Takayasu arteritis (TA), are worthwhile describing.
Differences between the pediatric and adult presentation of fibromuscular dysplasia: results from the US Registry
TLDR
In the United States Registry for FMD, pediatric FMD affects children from infancy throughout childhood and in children, FMD most commonly affects the renal vasculature, but also frequently involves the mesenteric arteries and abdominal aorta.
[Renovascular disease in children - a rare diagnosis with few symptoms].
TLDR
Children with severely elevated blood pressure as a result of renovascular disease often have unspecific or no symptoms and Invasive treatment may be considered in children and adolescents when standard treatment for hypertension is insufficient.
Clinical Course, Management, and Outcomes of Pediatric Takayasu Arteritis Initially Presenting with Hypertension: a 16-year overview.
TLDR
Most of c-TA has hypertension, presenting with a more quiescent disease without typical systemic and/or ischemia symptoms, more localized abdominal lesions, higher proportion of revascularizations and better event-free survival.
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