Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering.

@article{Izuhara2005RenoprotectivePO,
  title={Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering.},
  author={Yuko Izuhara and Masaomi Nangaku and Reiko Inagi and Naoto Tominaga and Toru Aizawa and Kiyoshi Kurokawa and Charles van Ypersele de Strihou and Toshio Miyata},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2005},
  volume={16 12},
  pages={3631-41}
}
Clinical studies have demonstrated that some antihypertensive agents provide renoprotection independent of BP lowering. Recent in vitro and in vivo studies evaluated the mechanisms involved in this protection. First, the in vitro effects of several angiotensin II type 1 receptor blockers (ARB), calcium channel blockers (CCB), and beta blockers (BB) on various mediators were compared: Formation of pentosidine (an advanced glycation end product), hydroxyl radical-induced formation of o-tyrosine… CONTINUE READING

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Iron accumulation in 3640 Journal of the American Society of Nephrology

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  • 2005
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