Renoprotective effects of (+)-catechin in streptozotocin-induced diabetic rat model.

@article{Chennasamudram2012RenoprotectiveEO,
  title={Renoprotective effects of (+)-catechin in streptozotocin-induced diabetic rat model.},
  author={Sudha P. Chennasamudram and Shashi K. Kudugunti and P. Boreddy and M. Moridani and T. Vasylyeva},
  journal={Nutrition research},
  year={2012},
  volume={32 5},
  pages={
          347-56
        }
}
Diabetic nephropathy is a complication of diabetes mellitus leading to end-stage renal disease. Oxidative stress and inflammation play a major role in the pathogenesis of diabetic nephropathy. Green tea, known for its antioxidant and anti-inflammatory properties, has been shown to be renoprotective. We hypothesized that (+)-catechin (CTN), a component of green tea, is responsible for the renoprotection. Our investigation of the therapeutic potential of CTN in streptozotocin-induced diabetic… Expand
Catechin Treatment Ameliorates Diabetes and Its Complications in Streptozotocin-Induced Diabetic Rats
(+)-Catechin ameliorates diabetic nephropathy by trapping methylglyoxal in type 2 diabetic mice.
Mechanisms of Herbal Nephroprotection in diabetes mellitus
Effect of catalpol on diabetic nephropathy in rats.
  • Z. Dong, C. Chen
  • Chemistry, Medicine
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
  • 2013
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