Renoprotective activity of benincasa cerifera fruit extract on ischemia/reperfusion-induced renal damage in rat.

@article{Bhalodia2009RenoprotectiveAO,
  title={Renoprotective activity of benincasa cerifera fruit extract on ischemia/reperfusion-induced renal damage in rat.},
  author={Yagnik S. Bhalodia and Nilesh R. Kanzariya and Rameshvar K. Patel and Natavarlal M. Patel and Jitendra D. Vaghasiya and Nurudin P. Jivani and Hitesh G Raval},
  journal={Iranian journal of kidney diseases},
  year={2009},
  volume={3 2},
  pages={80-5}
}
INTRODUCTION Evidence suggests that reactive oxygen species play a role in the pathophysiology of renal ischemia/reperfusion (I/R) injury. This study was designed to investigate the renoprotective activity of methanolic fruit extract of Benincasa cerifera in I/R-induced kidney failure in rats. MATERIALS AND METHODS Renal pedicles of 12 rats were occluded for 60 minutes followed by 24 hours of reperfusion. Six days prior to induction of I/R, 6 of the rats received Benincasa cerifera, 500 mg/kg… CONTINUE READING