Renoprotection persists after cessation of treatment with very low doses of perindopril in Lyon hypertensive rats

AbstractAim:The possibility that angiotensin-converting enzyme inhibitors can protect hypertensive kidneys independently of any blood pressure (BP) decrease remains a matter of controversy. The present study investigates this theory in Lyon genetically-hypertensive (LH) rats.Methods:Male rats were used in the present study and were untreated (controls) or… CONTINUE READING