Renin inhibitors as possible antihypertensive agents

Abstract

The blockade of the renin-angiotensin system by inhibition of angiotensin-converting enzyme has become an established principle in the treatment of hypertension. This has stimulated interest in the inhibition of renin, the enzyme which catalyzes the first and rate-limiting step in the formation of angiotensin II. During recent years, considerable progress… (More)
DOI: 10.1007/BF01728953

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