Renin inhibition in the treatment of diabetic kidney disease.

  title={Renin inhibition in the treatment of diabetic kidney disease.},
  author={Radko Komers},
  journal={Clinical science},
  volume={124 9},
Inhibition of the RAAS (renin-angiotensin-aldosterone system) plays a pivotal role in the prevention and treatment of diabetic nephropathy and a spectrum of other proteinuric kidney diseases. Despite documented beneficial effects of RAAS inhibitors in diabetic patients with nephropathy, reversal of the progressive course of this disorder or at least long-term stabilization of renal function are often difficult to achieve, and many patients still progress to end-stage renal disease. Incomplete… CONTINUE READING


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