Renin in the human kidney. Immunohistochemical localization.

@article{Celio1981ReninIT,
  title={Renin in the human kidney. Immunohistochemical localization.},
  author={Marco R. Celio and Tadashi Inagami},
  journal={Histochemistry},
  year={1981},
  volume={72 1},
  pages={1-10}
}
We have localized the enzyme renin (EC 3.4.99.19) in the normal adult human kidney by immunohistology. Serial paraffin sections of kidneys were incubated with renin antisera and then processed by the peroxidase-antiperoxidase method. Renin immunoreactivity was observed in the juxta-glomerular "epithelioid granular cells" (JEG-cells) in the wall of the afferent and rarely of the efferent vessel of the glomerulus. JEG-cells have long cytoplasmic processes penetrating between adjacent cells. This… CONTINUE READING