Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study.

@article{Suonsyrj2009ReninangiotensinSA,
  title={Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study.},
  author={Timo Suonsyrj{\"a} and Tuula Hannila-Handelberg and Heidi Fodstad and Kati M. Donner and Kimmo K. Kontula and Timo P Hiltunen},
  journal={American journal of hypertension},
  year={2009},
  volume={22 2},
  pages={169-75}
}
BACKGROUND Polymorphisms in genes coding for components of the renin-angiotensin system (RAS) and alpha-adducin (ADD1) have been reported to be associated with blood pressure (BP) responses to antihypertensive agents. The results, however, have not been consistent and most of the earlier studies have been small and lacked placebo-control. Therefore, the association of common polymorphisms in these genes with BP responses to four different antihypertensive drugs was analyzed in a controlled… CONTINUE READING
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