Renin-angiotensin system activation during severe OHSS: cause or effect?

  title={Renin-angiotensin system activation during severe OHSS: cause or effect?},
  author={Massimo Manno and Francesco Tomei},
  journal={Fertility and sterility},
  volume={89 2},
We are really concerned about the possibility of the implementation of such preventive approach for several reasons. First, the renin-angiotensin system activation and the correlation between renin activity and OHSS severity could be, probably, the effect and not the cause of this complication. In fact, every clinical condition characterized by hypovolemia leads to a secondary reactive hyperaldosteronism by renin-angiotensin cascade activation. Severe OHSS is a model of hypovolemia produced by… CONTINUE READING