Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies.

@article{Patel2017ReninangiotensinaldosteroneT,
  title={Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies.},
  author={Seema Patel and Abdur Rauf and Haroon Khan and Tareq Abu-Izneid},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2017},
  volume={94},
  pages={
          317-325
        }
}
Renin-angiotensin-aldosterone system (RAAS) is a vital system of human body, as it maintains plasma sodium concentration, arterial blood pressure and extracellular volume. Kidney-secreted renin enzyme acts on its substrate to form angiotensin II, a versatile effector peptide hormone. Every organ is affected by RAAS activation and the resultant hypertension, cell proliferation, inflammation, and fibrosis. The imbalance of renin and angiotensin II can result in an overwhelming number of chronic… CONTINUE READING
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