Renewal of the Holocrine Meibomian Glands by Label-Retaining, Unipotent Epithelial Progenitors


The meibomian and sebaceous glands secrete lipids to prevent desiccation of the ocular surface and skin, respectively. Precisely how these holocrine tissues regenerate is not well understood. To address this, we characterized keratin 5(+) (K5) label-retaining cells (LRCs) and the lineage tracing of keratin 14 (K14) progenitors in mouse meibomian glands… (More)
DOI: 10.1016/j.stemcr.2016.07.010


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