Renal vasodepressor mechanisms: the medullipin system

  title={Renal vasodepressor mechanisms: the medullipin system},
  author={E. Muirhead},
  journal={Journal of Hypertension},
  • E. Muirhead
  • Published 1993
  • Medicine
  • Journal of Hypertension
Renal vasodepressor hormone Medullipin I is the renomedullary vasodepressor hormone secreted by the renomedullary interstitial cells of the renal papilla. It is conveyed to the liver where it is converted to its active form, medullipin II. Medullipin II is a vasodilator that suppresses sympathetic tone and causes diuresis and natriuresis. Its actions are opposite to those of angiotensin II. These are feedback control systems. The secretion and conversion of medullipin is related to the… Expand
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