Renal tubule albumin transport.

@article{Gekle2005RenalTA,
  title={Renal tubule albumin transport.},
  author={Michael Gekle},
  journal={Annual review of physiology},
  year={2005},
  volume={67},
  pages={
          573-94
        }
}
Albumin is the most abundant protein in serum and contributes to the maintenance of oncotic pressure as well as to transport of hydrophobic molecules. Although albumin is a large anionic protein, it is not completely retained by the glomerular filtration barrier. In order to prevent proteinuria, albumin is reabsorbed along the proximal tubules by receptor-mediated endocytosis, which involves the binding proteins megalin and cubilin. Endocytosis depends on proper vesicle acidification… CONTINUE READING
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