Renal tubular effects of diuretics and X-ray contrast media. A comparative study of equimolar doses in healthy volunteers.


RATIONALE AND OBJECTIVES The isotonic nonionic contrast medium iodixanol has been shown to increase urinary enzyme excretion less than the hypertonic contrast medium iopentol. The authors investigated whether this could be caused by different molar loads using enzyme excretion after diuretic administration as a model. METHODS Matching molar doses of… (More)


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