Renal transplantation in systemic amyloidosis-importance of amyloid fibril type and precursor protein abundance.

@article{Pinney2013RenalTI,
  title={Renal transplantation in systemic amyloidosis-importance of amyloid fibril type and precursor protein abundance.},
  author={Jennifer H. Pinney and Helen Lachmann and Prayman T. Sattianayagam and Simon D. J. Gibbs and Ashutosh D Wechalekar and Christopher Paul Venner and Carol J. Whelan and Janet Anne Gilbertson and D Rowczenio and Philip N. Hawkins and Julian D. Gillmore},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2013},
  volume={13 2},
  pages={433-41}
}
Renal transplantation remains contentious in patients with systemic amyloidosis due to the risk of graft loss from recurrent amyloid and progressive disease. Outcomes were sought among all patients attending the UK National Amyloidosis Centre who received a renal transplant (RTx) between January 1978 and May 2011. A total of 111 RTx were performed in 104 patients. Eighty-nine percent of patients with end-stage renal disease (ESRD) due to hereditary lysozyme and apolipoprotein A-I amyloidosis… CONTINUE READING