Renal transplantation: basic concepts and evolution of therapy.

  title={Renal transplantation: basic concepts and evolution of therapy.},
  author={William E. Braun},
  journal={Journal of clinical apheresis},
  volume={18 3},
Within the last 5 years, dramatic changes in the area of renal transplantation have occurred. There have been shifts in the dominant types of rejection, and in the types and utilization of immunosuppressants. Hyperacute rejection is now rarely seen, and acute cellular rejection within the first 6 to 12 months has been reduced to about 10%. However, humoral/antibody-mediated rejection has become a more prevalent problem. In the area of immunosuppressants, the ability to reduce acute cellular… CONTINUE READING