Renal toxicity of lisinopril and rosuvastatin, alone and in combination, in Wistar rats.

Abstract

The aim of study was to evaluate the effect of commonly used lisinopril, rosuvastatin and their combined action on site-specific nephrotoxicity in rats using clusterin and microalbumin nephrotoxic biomarkers and other related parameters using oral gavage. Rosuvastatin at 2 different doses showed increase in urinary microalbumin levels whereas lisinopril and… (More)
DOI: 10.1177/1091581811415293

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