Renal sugar transport in the winter flounder. VI. Reabsorption of D-mannose.

@article{Pritchard1982RenalST,
  title={Renal sugar transport in the winter flounder. VI. Reabsorption of D-mannose.},
  author={John B. Pritchard and Gerhard Booz and Arno{\vs}t Kleinzeller},
  journal={The American journal of physiology},
  year={1982},
  volume={242 4},
  pages={F415-22}
}
The transport of D-mannose (Man) in flounder kidney was studied using renal clearance techniques in vivo and brush border membrane (BBM) vesicles in vitro. At plasma concentrations of 50-100 microM Man, the winter flounder (Pseudopleuronectes americanus) reabsorbed up to 70% of the filtered sugar. Man phosphates, but not free Man, accumulated in renal cells. Reabsorption of Man was reduced by phlorizin, D-glucose, methyl-alpha-D-glucoside, methyl-alpha-D-mannoside, and 2-deoxy-D-glucose. In BBM… CONTINUE READING