Renal replacement therapy in acute kidney injury: controversy and consensus


Acute kidney injury (AKI) is a common complication among critically ill patents, and 5% of intensive care unit (ICU) patients require initiation of renal replacement therapy (RRT). In recent years, clinical trials have provided evidence-based guidance for some important aspects of RRT management in patients with AKI, such as dialysis dosing and approaches to anticoagulation in patients undergoing continuous RRT. However, there remain many areas of uncertainty, and delivery of RRT in the ICU requires clinical judgment, flexibility, and an understanding of dialysis principles. This article reviews the components of RRT prescription and provides an update on best practices.

DOI: 10.1016/j.ccc.2016.12.003

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@inproceedings{Ronco2015RenalRT, title={Renal replacement therapy in acute kidney injury: controversy and consensus}, author={Claudio Ronco and Zaccaria Ricci and Daniel De Backer and John A. Kellum and Fabio Silvio Taccone and M Joannidis and Peter Pickkers and Vincenzo Cantaluppi and Franco Turani and Patrick Saudan and Rinaldo Bellomo and Olivier Joann{\`e}s-Boyau and Massimo Antonelli and Didier M. Payen and J R Prowle and Jean-Louis Vincent}, booktitle={Critical care clinics}, year={2015} }