Renal protective effect of strict blood pressure control with enalapril therapy.

@article{Bauer1987RenalPE,
  title={Renal protective effect of strict blood pressure control with enalapril therapy.},
  author={John H. Bauer and Garry P. Reams and Sunder M Lal},
  journal={Archives of internal medicine},
  year={1987},
  volume={147 8},
  pages={1397-400}
}
The effect of strict blood pressure control on progression of renal disease in patients with essential hypertension has not been well defined. We have followed prospectively for three years 23 patients with essential hypertension. Blood pressure was well controlled on either enalapril or enalapril-hydrochlorothiazide therapy. Yearly assessment of renal function revealed no change in glomerular filtration rate as assessed by creatinine or inulin clearance, and a sustained 17% increase in… CONTINUE READING