Renal prostaglandin E2 synthesis in the Brattleboro homozygous diabetes insipidus rat.

The effect of vasopressin (VP) on prostaglandin (PG) synthesis in the renal collecting tubule remains equivocal. To further address this issue, the present study determined the effects of chronic absence of VP on renal medullary collecting tubule PG synthesis. Prostaglandin E2 (PGE2) synthesis was measured in both inner and outer medullary slices and… CONTINUE READING