Renal primary cilia lengthen after acute tubular necrosis.

  title={Renal primary cilia lengthen after acute tubular necrosis.},
  author={Elizabeth Verghese and Sharon D Ricardo and Raphael Weidenfeld and Junli Zhuang and Prudence A. Hill and Robyn G. Langham and James A Deane},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={20 10},
Renal primary cilia are sensory antennas required for the maintenance of normal epithelial differentiation and proliferation in the kidney, but they also have a potential role in epithelial differentiation during renal injury and repair. In mice, tubular damage causes an increase in the length of renal cilia, which may modify their sensory sensitivity during repair. Here, we investigated whether the alteration of renal cilium length during renal injury is clinically relevant. Using biopsies of… CONTINUE READING


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