Renal pharmacology of GR138950, a novel non-peptide angiotensin AT1 receptor antagonist.

Abstract

This paper describes the renal pharmacology of the novel, specific, non-peptide angiotensin AT1 receptor antagonist, GR138950 (1-[[3-bromo-2-[2-[[(trifluoromethyl) sulphonyl] amino] phenyl]-5-benzofuranyl] methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5- carboxamide). When administered to anaesthetised salt-replete dogs, GR138950 caused renal vasodilatation… (More)

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@article{Clark1995RenalPO, title={Renal pharmacology of GR138950, a novel non-peptide angiotensin AT1 receptor antagonist.}, author={K. L. Clark and M. J. Robertson and G. M. Drew}, journal={European journal of pharmacology}, year={1995}, volume={280 2}, pages={195-203} }