Renal medullary interstitial infusion ofl-arginine prevents hypertension in Dahl salt-sensitive rats.

Abstract

Studies were designed to examine the effects of renal medullary interstitial infusion of l-arginine (l-Arg) on the development of high-salt-induced hypertension in Dahl salt-sensitive/Rapp (DS) rats. The threshold dose of l-Arg (300 μg ⋅ kg-1 ⋅ min-1) that increased the renal medullary blood flow without altering the cortical blood flow was first determined… (More)
DOI: 10.1152/ajpregu.1998.275.5.R1667

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