Renal insufficiency coexisting with heart failure is related to elevated sympathetic nerve activity.

@article{Oda2010RenalIC,
  title={Renal insufficiency coexisting with heart failure is related to elevated sympathetic nerve activity.},
  author={Yoshitaka Oda and Shuji Joho and Daisuke Harada and Tadakazu Hirai and Hidetsugu Asanoi and Hiroshi Inoue},
  journal={Autonomic neuroscience : basic & clinical},
  year={2010},
  volume={155 1-2},
  pages={104-8}
}
We investigated whether coexisting renal insufficiency (RI) is associated with elevated sympathetic activity in patients with heart failure (HF). Resting muscle sympathetic nerve activity (MSNA) was determined in 101 patients with HF (ejection fraction<0.45) and 8 patients with RI but without HF (RI group). Diagnosis of RI was made of glomerular filtration rates <60ml/min/1.73m(2) estimated using the simplified Modification of Diet in Renal Disease equation. Of 101 patients, 45 had RI (HFRI… CONTINUE READING

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