Renal hemodynamic effects elicited by acute cyclooxygenase-2 inhibition are not related to angiotensin II levels.

@article{Salazar2010RenalHE,
  title={Renal hemodynamic effects elicited by acute cyclooxygenase-2 inhibition are not related to angiotensin II levels.},
  author={Francisco J. Salazar and Maria Teresa Llin{\'a}s},
  journal={American journal of physiology. Renal physiology},
  year={2010},
  volume={299 5},
  pages={F952-3}
}
NUMEROUS STUDIES HAVE DEMONSTRATED that cyclooxygenase-2 (COX-2) is involved in the regulation of renal function. It has also been shown that renal COX-2 expression and activity change in response to physiological stimuli, such as variations in sodium intake, and in response to changes in several vasoactive hormones (6, 9). The importance of COX-2-derived metabolites in regulating renal function in volume-contracted states is supported by studies showing that COX-2 expression is enhanced in the… CONTINUE READING