Renal handling of drugs and amino acids after impairment of kidney or liver function--influences of maturity and protective treatment.

Abstract

Renal tubular cells are involved both in secretion and in reabsorption processes within the kidney. Normally, most xenobiotics are secreted into the urine at the basolateral membrane of the tubular cell, whereas amino acids are reabsorbed quantitatively at the luminal side. Under different pathological or experimental circumstances, these transport steps… (More)

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