Renal haemodynamics and tubular function in human pregnancy.

  title={Renal haemodynamics and tubular function in human pregnancy.},
  author={William Dunlop and John M. Davison},
  journal={Bailliere's clinical obstetrics and gynaecology},
  volume={1 4},
In human pregnancy, effective renal plasma flow and glomerular filtration rate increase to levels 50-80% above non-pregnant values. The increments occur shortly after conception, persist throughout the second trimester and reduce slightly in late pregnancy. The hyperfiltration of pregnancy does not seem to be a potentially damaging process. The increased excretion of glucose and other nutrients, as well as uric acid and protein, is related in part to altered tubular function. Renal physiology… CONTINUE READING

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