Renal glutaminases: Diamox inhibition of glutamyltransferase.


Ammonia (NH3) production by the rat kidney was studied after an acute administration of acetazolamide (Diamox). Diamox reduced renal ammonia release (renal vein NH3 + urine NH3 - arterial NH3) 60 PERCENT IN The intact functioning kidney. Ammonia production by whole-kidney homogenates was decreased by Diamox, confirming the drug's action as inhibiting… (More)


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@article{Phenix1975RenalGD, title={Renal glutaminases: Diamox inhibition of glutamyltransferase.}, author={P Phenix and Tomas C. Welbourne}, journal={The American journal of physiology}, year={1975}, volume={228 4}, pages={1269-75} }