74 Citations
Ionic control or renal gluconeogenesis. 3. The effects of changes in pH, pCO2, and bicarbonate concentration.
- BiologyBiochimica et biophysica acta
- 1973
Ioni control of renal gluconeogenesis. I. The interrelated effect of calcium and hydrogen ions.
- Biology, Computer ScienceBiochimica et biophysica acta
- 1973
Ionic control of renal gluconeogenesis. IV. Effect of extracellular phosphate concentration.
- BiologyBiochimica et biophysica acta
- 1973
Ionic control of renal gluconeogenesis. II. The effects of Ca2+ and H+ upon the response to parathyroid hormone and cyclic AMP.
- BiologyBiochimica et biophysica acta
- 1973
Substrate-dependent effect of 1-34 human parathyroid hormone fragment, dibutyryl cAMP and cAMP on gluconeogenesis in rabbit renal tubules.
- Biology, Computer ScienceBiochimica et biophysica acta
- 1986
Effect of parathyroid hormone and calcium ions on substrate oxidation by isolated glomeruli of the rat.
- Biology, ChemistryBiochimica et biophysica acta
- 1981
Relationship between L-alanine and sodium ion transport in isolated renal tubules.
- BiologyBiochimica et biophysica acta
- 1975
Localization and role of pyruvate kinase isoenzymes in the regulation of carbohydrate metabolism and pyruvate recycling in rat kidney cortex.
- Biology, Computer ScienceBiochimica et biophysica acta
- 1986
Effects of Ca2+ and Mg2+ upon amino acid transport in rat renal cortex slices.
- Biology, ChemistryBiochimica et biophysica acta
- 1971
Effects of glucagon and cyclic AMP on ion fluxes in the perfused liver.
- BiologyBiochimica et biophysica acta
- 1972
References
SHOWING 1-10 OF 27 REFERENCES
Renal gluconeogenesis: effects of parathyroid hormone and dibutyryl 3',5'-AMP.
- BiologyBiochimica et biophysica acta
- 1970
Effect of adenosine 3',5'-monophosphate on production of glucose and ammonia by renal cortex.
- BiologyThe Journal of clinical investigation
- 1969
Observations suggest that cyclic AMP accelerates a rate-limiting gluconeogenic reaction between oxalacetate and the triose phosphates, which is consistent with a previously advanced hypothesis that cortical gluconeogenesis, ammonia production, and glutamate concentration may be interdependent.
Acid-base alterations and renal gluconeogenesis: effect of pH, bicarbonate concentration, and PCO2.
- BiologyThe Journal of clinical investigation
- 1967
P pH, rather than CO(2) tension or [HCO(3) (-)], is the most important acid-base variable affecting renal gluconeogenesis, and the findings suggest that a decrease in extracellular fluid pH enhances renal gluc oneogenesis through direct stimulation of one of the rate-limiting reactions involved in the conversion of oxalacetate to glucose.
Regulation of glutamine metabolism in vitro by bicarbonate ion and pH.
- BiologyThe Journal of clinical investigation
- 1969
The increase in citrate clearance in metabolic alkalosis and the increase in glutamine utilization and ammonium production in metabolic acidosis reflect the operation of the same underlying biochemical mechanism, suggests that one control mechanism affects the metabolism of both citrate and glutamine.
Regulation of renal citrate metabolism by bicarbonate ion and pH: observations in tissue slices and mitochondria.
- Biology, MedicineThe Journal of clinical investigation
- 1967
The inhibition of citrate oxidation caused by increasing pH and [HCO(3) (-)] in slices of renal cortex and kidney mitochondria is an in vitro representation of the inhibition ofcitrate reabsorption in the nephron that occurs in metabolic alkalosis.
Renal metabolic response to acid base changes. I. Enzymatic control of ammoniagenesis in the rat.
- BiologyThe Journal of clinical investigation
- 1969
It is proposed that the increase of PEPCK activity is the key event in the ammoniagenesis and gluconeogenesis which follow on metabolic acidosis, which is constantly related to increases of urinary ammonia.
EFFECT OF METAL IONS ON IN VITRO GLUCONEOGENESIS IN RAT KIDNEY CORTEX SLICES.
- BiologyThe American journal of physiology
- 1965
Evidence is presented as to the possible significance of metal ions in regulating carbohydrate metabolism and the stimulation of gluconeogenesis from α-keto acids is comparable for both Ca and Mn ++.
Parathyroid hormone and mitochondrial metabolism. Specificity, sensitivity, and physiological correlates.
- Biology, MedicineThe Journal of biological chemistry
- 1967
Pathways of ammonia metabolism in the intact functioning kidney of the dog.
- BiologyThe Journal of clinical investigation
- 1967
Studies in which (15)N-labeled precursors of urinary ammonia were infused into the artery of an intact functioning kidney of an acidotic dog have led to the following conclusions: Preformed ammonia…
Concentrations of Metabolic Intermediates in Kidneys of Rats with Metabolic Acidosis
- BiologyNature
- 1968
The results presented here represent an attempt to define that step that in acidosis there is acceleration of one of the steps in the gluconeogenesis pathway distal to oxaloacetate.