Renal gluconeogenesis: effects of Ca2+ and H+.

@article{Nagata1970RenalGE,
  title={Renal gluconeogenesis: effects of Ca2+ and H+.},
  author={Naokazu Nagata and Howard Rasmussen},
  journal={Biochimica et biophysica acta},
  year={1970},
  volume={215 1},
  pages={
          1-16
        }
}
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74 Citations
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74 Citations

Ionic control or renal gluconeogenesis. 3. The effects of changes in pH, pCO2, and bicarbonate concentration.

Ioni control of renal gluconeogenesis. I. The interrelated effect of calcium and hydrogen ions.

Ionic control of renal gluconeogenesis. IV. Effect of extracellular phosphate concentration.

Ionic control of renal gluconeogenesis. II. The effects of Ca2+ and H+ upon the response to parathyroid hormone and cyclic AMP.

Substrate-dependent effect of 1-34 human parathyroid hormone fragment, dibutyryl cAMP and cAMP on gluconeogenesis in rabbit renal tubules.

Effect of parathyroid hormone and calcium ions on substrate oxidation by isolated glomeruli of the rat.

Relationship between L-alanine and sodium ion transport in isolated renal tubules.

Localization and role of pyruvate kinase isoenzymes in the regulation of carbohydrate metabolism and pyruvate recycling in rat kidney cortex.

Effects of Ca2+ and Mg2+ upon amino acid transport in rat renal cortex slices.

Effects of glucagon and cyclic AMP on ion fluxes in the perfused liver.

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The inhibition of citrate oxidation caused by increasing pH and [HCO(3) (-)] in slices of renal cortex and kidney mitochondria is an in vitro representation of the inhibition ofcitrate reabsorption in the nephron that occurs in metabolic alkalosis.

Renal metabolic response to acid base changes. I. Enzymatic control of ammoniagenesis in the rat.

It is proposed that the increase of PEPCK activity is the key event in the ammoniagenesis and gluconeogenesis which follow on metabolic acidosis, which is constantly related to increases of urinary ammonia.

EFFECT OF METAL IONS ON IN VITRO GLUCONEOGENESIS IN RAT KIDNEY CORTEX SLICES.

Evidence is presented as to the possible significance of metal ions in regulating carbohydrate metabolism and the stimulation of gluconeogenesis from α-keto acids is comparable for both Ca and Mn ++.

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Studies in which (15)N-labeled precursors of urinary ammonia were infused into the artery of an intact functioning kidney of an acidotic dog have led to the following conclusions: Preformed ammonia…

Concentrations of Metabolic Intermediates in Kidneys of Rats with Metabolic Acidosis

The results presented here represent an attempt to define that step that in acidosis there is acceleration of one of the steps in the gluconeogenesis pathway distal to oxaloacetate.