Renal functional reserve in healthy elderly subjects.

  title={Renal functional reserve in healthy elderly subjects.},
  author={Danilo Fliser and Martin G. Zeier and Robert L. Nowack and Eberhard Ritz},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={3 7},
The increase in GFR after an amino acid (AA) load, the so-called renal functional reserve, is impaired in the aged rat. Whether the renal functional reserve predicts the progression of renal disease in humans is controversial, but it is possible that age-related alterations of renal hemodynamics are relevant for the evolution of renal disease in the elderly… CONTINUE READING