Renal function with cyclosporine C2 monitoring, enteric-coated mycophenolate sodium and basiliximab: a 12-month randomized trial in renal transplant recipients.

@article{Cibrik2007RenalFW,
  title={Renal function with cyclosporine C2 monitoring, enteric-coated mycophenolate sodium and basiliximab: a 12-month randomized trial in renal transplant recipients.},
  author={Diane M. Cibrik and Herwig-Ulf Meier-Kriesche and Barbara Bresnahan and You Min Wu and Goran Klintmalm and Clifton E Kew and P. C. Kuo and John Whelchel and David G Cohen and Prabakar Baliga and Enver Akalin and Enrico Benedetti and Francis J. Wright and Bonnie Lieberman and Bettina Ulbricht and Stephen C Jensik},
  journal={Clinical transplantation},
  year={2007},
  volume={21 2},
  pages={192-201}
}
BACKGROUND Cyclosporine exposure, as estimated by the area under the curve (AUC), predicts outcomes in renal transplantation. Cyclosporine concentration at two h post-dose (C(2)) has been shown to be the most reliable, single-point surrogate marker for AUC. The objective of this study was to measure renal function beyond month 2 post-transplant using two different C(2) maintenance targets in combination with enteric-coated mycophenolate sodium (EC-MPS), corticosteroids, and basiliximab… CONTINUE READING

Citations

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