Renal function and glucose transport in male and female mice with diet-induced type II diabetes mellitus.

@article{Noonan2000RenalFA,
  title={Renal function and glucose transport in male and female mice with diet-induced type II diabetes mellitus.},
  author={William T Noonan and Robert O. Banks},
  journal={Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine},
  year={2000},
  volume={225 3},
  pages={221-30}
}
The aim of this study was to measure cardiovascular and renal function, including the renal transport capacity for glucose, in male and female C57BL/6J mice with diet-induced Type II diabetes mellitus. Typical of Type II diabetes, mice fed a high-fat, high-simple carbohydrate diet for 3 months were obese (45-65 g), hyperglycemic (138-259 mg%), and hyperinsulinemic (1.8-15.06 ng/ml); significant gender differences were observed in all cases. Based on systolic pressure measurements in conscious… CONTINUE READING

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