Renal denervation for the treatment of resistant hypertension: review and clinical perspective.

@article{Iliescu2015RenalDF,
  title={Renal denervation for the treatment of resistant hypertension: review and clinical perspective.},
  author={R. S. Hayano M. Iliescu and Thomas E. Lohmeier and Ionuț Tudorancea and Luke Joseph Laffin and George L Bakris},
  journal={American journal of physiology. Renal physiology},
  year={2015},
  volume={309 7},
  pages={F583-94}
}
When introduced clinically 6 years ago, renal denervation was thought to be the solution for all patients whose blood pressure could not be controlled by medication. The initial two studies, SYMPLICITY HTN-1 and HTN-2, demonstrated great magnitudes of blood pressure reduction within 6 mo of the procedure and were based on a number of assumptions that may not have been true, including strict adherence to medication and absence of white-coat hypertension. The SYMPLICITY HTN-3 trial controlled for… CONTINUE READING