Renal complications and scleroderma renal crisis.

  title={Renal complications and scleroderma renal crisis.},
  author={Christopher P. Denton and Giovanni Lapadula and Luc Mouthon and Ulf Mueller-Ladner},
  volume={48 Suppl 3},
Scleroderma renal crisis (SRC) occurs in 5-10% of SSc patients, who may present with an abrupt onset of hypertension, acute renal failure, headaches, fevers, malaise, hypertensive retinopathy, encephalopathy and pulmonary oedema. Patients at greatest risk of developing SRC are those with diffuse cutaneous or rapidly progressive forms of SSc, and treatment with a recently commenced high dose of corticosteroid. Laboratory tests may demonstrate hypercreatinaemia, microangiopathic haemolytic… CONTINUE READING


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