Renal clearance of uric acid is linked to insulin resistance and lower excretion of sodium in gout patients

@article{PerezRuiz2015RenalCO,
  title={Renal clearance of uric acid is linked to insulin resistance and lower excretion of sodium in gout patients},
  author={Fernando Perez-Ruiz and Maria Angeles Aniel-Quiroga and Ana Mar{\'i}a Herrero-Beites and Sandra Pamela Chinchilla and Gorka Garcia Erauskin and Tony R. Merriman},
  journal={Rheumatology International},
  year={2015},
  volume={35},
  pages={1519-1524}
}
AbstractInefficient renal excretion of uric acid is the main pathophysiological mechanism for hyperuricemia in gout patients. Polymorphisms of renal tubular transporters linked with sodium and monosaccharide transport have yet to be demonstrated. We intended to evaluate the impact of insulin resistance, evaluated with the homeostasis model assessment (HOMA), through a transversal study of non-diabetic patients with gout, with normal renal function, not treated with any medication but colchicine… CONTINUE READING
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