Renal autoregulation and passive pressure-flow relationships in diabetes and hypertension.

@article{Hill2010RenalAA,
  title={Renal autoregulation and passive pressure-flow relationships in diabetes and hypertension.},
  author={J V Hill and Glenne Findon and Rebecca J. Appelhoff and Zoltan Huba Endre},
  journal={American journal of physiology. Renal physiology},
  year={2010},
  volume={299 4},
  pages={
          F837-44
        }
}
  • J. Hill, G. Findon, +1 author Z. Endre
  • Published 1 October 2010
  • Biology, Medicine
  • American journal of physiology. Renal physiology
We investigated renal hemodynamics in isolated, perfused kidneys from rat models of diabetes and hypertension. Autoregulation and passive vascular responses were measured using stepped pressure ramps in the presence of angiotensin II (pEC50) or papaverine (0.1 mM), respectively. Male diabetic heterozygote m(Ren2)27 rats were compared with three male control groups: nondiabetic, normotensive Sprague-Dawley (SD) rats; nondiabetic, hypertensive heterozygote m(Ren2)27 rats; and diabetic… 
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11 Citations
Background Citations
6
Methods Citations
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Results Citations
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11 Citations

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Citation Type

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TLDR
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Impact of individualized target mean arterial pressure for septic shock resuscitation on the incidence of acute kidney injury: a retrospective cohort study
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The incidence of AKI was lowest among those whose post-resuscitation MAP was closest to or higher than their pre-admission MAP, and among patients with a history of hypertension, which was the lowest quartile in this cohort.
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