Renal artery denervation for the treatment of resistant hypertension. Update after Medtronic announcement that its Symplicity HTN3 study failed to meet its primary efficacy end point.

@article{Sapoval2014RenalAD,
  title={Renal artery denervation for the treatment of resistant hypertension. Update after Medtronic announcement that its Symplicity HTN3 study failed to meet its primary efficacy end point.},
  author={Marc R. Sapoval and Michel Azizi},
  journal={Diagnostic and interventional imaging},
  year={2014},
  volume={95 4},
  pages={353-4}
}
Catheter-based renal denervation consists of delivering radiofrequency (RF) energy or ultrasound to interrupt afferent and efferent sympathetic nerve fibres which run through the renal artery adventitia which, together with other systems, contribute to regulating arterial blood pressure. The results of the first Symplicity HTN2 study using a unipolar RF… CONTINUE READING